tamoxifen's examples

  • Tamoxifen - Tamoxifen blocks the actions of estrogen, a female hormone. Certain types of breast cancer require estrogen to grow. - Do not use this medication without telling your doctor if you are pregnant. It could cause harm to the unborn baby. — “Tamoxifen - Side Effects, Dosage, Interactions - Drugs”,
  • Tamoxifen (Nolvadex) blocks the effects of estrogen hormone in the body. Tamoxifen is most commonly used to treat breast cancer in women or men. This drug may reduce the chance of breast cancer coming back in women previously treated with surgery. — “Tamoxifen”,
  • Tamoxifen, Causes of Tamoxifen resistance, adverse effects of tamoxifen, tamoxifen and aromatase inhibitors, botanicals and nutrients that synergize with tamoxifen. — “Tamoxifen”,
  • Tamoxifen also slows or stops the growth of cancer cells present in the body. Tamoxifen is classified as a selective estrogen receptor modulator. — “Tamoxifen and Breast Cancer”,
  • Tamoxifen Citrate Tablets, a nonsterodial antiestrogen, are for oral administration and contain 15.2 mg of Tamoxifen Citrate (equivalent to 10 mg of tamoxifen) Tamoxifen inhibits the induction of rat mammary carcinoma induced by. — “DES-like"”,
  • tamoxifen n. A nonsteroidal estrogen antagonist used in the treatment of advanced breast cancer in women whose tumors are estrogen-dependent and. — “tamoxifen: Definition from ”,
  • Tamoxifen, also known as Nolvadex, is a selective estrogen receptor modulator (SERM) which is used in the treatment and prevention of breast cancer. Tamoxifen works by interfering with the estrogen activity. Estrogen promotes that growth of. — “Tamoxifen”,
  • Tamoxifen is an antagonist of the estrogen receptor in breast tissue via its active metabolite, hydroxytamoxifen. Tamoxifen is metabolized into compounds that also bind to the estrogen receptor but do not activate it. — “Tamoxifen - Wikipedia, the free encyclopedia”,
  • Learn about the prescription medication Nolvadex (Tamoxifen Citrate), drug uses, dosage, side effects, drug interactions, warnings, reviews and patient labeling. — “Nolvadex (Tamoxifen Citrate) Drug Information: User Reviews”,
  • Tamoxifen is known to be a human carcinogen based on sufficient However, there also is conclusive evidence that tamoxifen therapy. reduces the risk of contralateral breast cancer in women with a. — “Tamoxifen CAS No. 10540-29-1”, ntp.niehs.nih.gov
  • Once praised for its benefits in preventing breast cancer recurrence, the lucrative pharmaceutical drug tamoxifen is now implicated in causing dangerous side-effects, including other types of cancers. — “Tamoxifen - A Major Medical Mistake?”, all-
  • Tamoxifen may be given as adjuvant therapy (treatment after successful surgery) in women or men with lymph node negative or lymph node positive breast cancer. Cancers with positive estrogen and progesterone receptors are more likely to benefit from tamoxifen. — “Tamoxifen, Novaldex - Chemotherapy Drugs, Chemo Drug Side Effects”,
  • Tamoxifen is now the number one recommended drug treatment for women recovering from breast cancer. With half a billion dollars (US) in annual revenues1, it is currently used by more women with breast cancer than any other prescription drug.2. — “InnerSelf: Beware! Tamoxifen”,
  • Tamoxifen may cause cancer of the uterus (womb), strokes, and blood clots in the lungs. If you need to take tamoxifen to treat breast cancer, the benefits of tamoxifen outweigh the risks. — “Tamoxifen: MedlinePlus Drug Information”, nlm.nih.gov
  • Tamoxifen symptoms, causes, diagnosis, and treatment information for Tamoxifen (Human carcinogen -Tamoxifen) with alternative diagnoses, full-text book chapters, misdiagnosis, research treatments, prevention, and prognosis. — “Tamoxifen - ”,
  • Information on many different cancers includes symptoms, cancer detection and prevention, and treatment options. Tamoxifen also is used for the treatment of women following surgery and radiation for a less common type of breast cancer called ductal carcinoma in situ (DCIS or intraductal carcinoma). — “tamoxifen - Cancer Information (Cancers, Symptoms, Treatment”,
  • Tamoxifen PDF, 137KB Tamoxifen (Nolvadex) has been used for over 20 years to treat breast cancers that are hormone-receptor positive . Figure 5.6 below illustrates how tamoxifen works: it attaches to. — “Susan G. Komen for the Cure | Understanding Breast Cancer”, ww5
  • Detailed information on tamoxifen, including indications for use, possible benefits, and potential side effects. — “Tamoxifen - New York Presbyterian Hospital”,
  • A fact sheet that describes the action, risks, benefits, and side effects of tamoxifen, a drug that interrupts the hormone estrogen and its connection to breast cancer. National Cancer Institute Fact Sheet 7.16. — “Tamoxifen: Questions and Answers - National Cancer Institute”, cancer.gov
  • Tamoxifen - Tamoxifen is a SERM (Selective Estrogen Receptor Modulators) used for breast cancer treatment. — “Tamoxifen”,
  • Tamoxifen (Soltamox) blocks the actions of estrogen and is used to treat and prevent some types of breast cancer. Includes tamoxifen side effects, interactions and indications. — “Tamoxifen Information from ”,
  • Find patient medical information for Tamoxifen Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. — “Tamoxifen Oral : Uses, Side Effects, Interactions, Pictures”,

related videos for tamoxifen

  • Zinc(II) ion mediates tamoxifen-induced autophagy and cell death in MCF-7 breast cancer cell line From the Springer article: Zinc(II) ion mediates tamoxifen-induced autophagy and cell death in MCF-7 breast cancer cell line by: Hwang, Jung Jin; Kim, Ha Na; Kim, Jean; Cho, Dong-Hyung; Kim, Mi Joung; Kim, Yong-Sook; Kim, Yunha; Park, Sung-Jin; Koh, Jae-Young; Live cell confocal microscopic images (1 minutes/frame) of a MCF-7 cell stained with FluoZin-3. Cells were treated with 17 μM tamoxifen and images were obtained from z-series collection (33 z-section images of 1 μm thickness) for 90 minutes. (AVI 483 kb) Journal: BioMetals Vol. 23 Issue 6 DOI: 10.1007/s10534-010-9346-9 Published: 2010-11-08
  • Happy Tamoxifen Day! - my story http - my art In this video: Starting Tamoxifen! Finally.
  • AACR 2010: Preventive treatment for breast cancer Dr Judy Garber, of the Dana Farber Cancer Institute in Boston, USA, talks about the STAR trial, which looked at tamoxifen versus raloxifene as preventive treatment to lower breast cancer risk in high risk post-menopausal women. Speaking at the 2010 annual AACR conference.
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  • How your bra can kill you The connection between breast cancer and bras. Find out more at breast cancer bra push up natural alternative prevention lymph nodes lymphatic system Erika Mizrahi tamoxifen mammogram oncology tumor hormone
  • EBCC6: Epigenetics in cancer care and predicting response to tamoxifen. Prof. Romano Danesi Internal Medicine, University of Pisa Epigenetics in cancer care and predicting response to tamoxifen.
  • Zinc(II) ion mediates tamoxifen-induced autophagy and cell death in MCF-7 breast cancer cell line From the Springer article: Zinc(II) ion mediates tamoxifen-induced autophagy and cell death in MCF-7 breast cancer cell line by: Hwang, Jung Jin; Kim, Ha Na; Kim, Jean; Cho, Dong-Hyung; Kim, Mi Joung; Kim, Yong-Sook; Kim, Yunha; Park, Sung-Jin; Koh, Jae-Young; Live cell confocal microscopic images (2 minutes/frame) of a MCF-7 cell stained with FluoZin-3. Cells were treated with 17 μM tamoxifen and images were obtained from z-series collection (38 z-section images of 1 μm thickness) for 86 minutes. (AVI 170 kb) Journal: BioMetals Vol. 23 Issue 6 DOI: 10.1007/s10534-010-9346-9 Published: 2010-11-08
  • How Do Tamoxifen and Femara Fight Breast Cancer? Hormone therapy, explains breast surgeon Amber Guth, stops estrogen from binding to cancer cells.
  • Dr John Hawse, Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine From 31st San Antonio Breast Cancer Symposium - Endoxifen levels in Breast Cancer patients and testing for CYP2D6 Patients receiving tamoxifen therapy who can produce high levels of endoxifen have better survival than those producing low levels - why is this? Test needed for patients with CYP2D6 gene prior to administering tamoxifen
  • Insidermedicine In Depth - December 7, 2010 - Breast Cancer/Ductal Carcinoma In Situ Both radiation therapy and the anticancer drug tamoxifen reduce the risk of having a breast cancer event among women who have had surgery to remove ductal carcinoma in situ, according to an update of a long-term trial published in the Lancet. Here is some information about ductal carcinoma in situ: • It is an early form of breast cancer in which the disease has not yet invaded the breast • "Ductal" means that the cancer remains inside the milk ducts and "in-situ" means it has not spread anywhere else • While the condition can be successfully cured with surgery, women with this condition are at an increased risk for developing invasive breast cancer later on. Researchers from the University of London randomly assigned over 1700 women who had undergone surgery to completely remove ductal carcinoma in situ to receive radiation therapy, tamoxifen, both treatments, or neither. After an average follow-up period of nearly 13 years, radiation therapy was found to reduce the risk of developing any breast cancer event by 59%. The treatment also reduced the risk of developing invasive breast cancer in the originally affected breast by 68% and recurrent ductal carcinoma in situ in the affected breast by 62%. Tamoxifen treatment reduced the risk of developing another breast cancer event by 29%, the risk of developing recurrent ductal carcinoma in situ in the same breast by 30%, and a tumor in the unaffected breast by 56%. We spoke with Dr. Jack Cuzick, one of the investigators of this ...
  • Endocrine Therapy, Tamoxifen & Aromatase Inhibitors Joanne Mortimer, MD, Director of the Womens Cancers Program at City of Hope Comprehensive Cancer Center, Duarte, California
  • Triple Negative Breast Cancer Triple negative breast cancer is an aggressive type of breast cancer in which the tumor cells lack receptors for estrogen, progesterone and the HER2 protein on their surfaces. Because the tumor cells lack these receptors, treatments such as hormone therapy, like tamoxifen and aromatase inhibitors, or drugs that target HER2, like Herceptin, are not effective. In this video, Dr. Sara Chumsri, a member of the UMGCC Breast Evaluation and Treatment Program, discusses triple negative breast cancer and some of the promising new research underway to develop new therapies to successfully treat this type of breast cancer. Related Links: Dr. Sara Chumsri www.umm.edu University of Maryland Greenebaum Cancer Center Breast Evaluation and Treatment Program Audio and Video Library www.umm.edu Information for Patients Distributed by Tubemogul.
  • Tamoxification! Life on Tamoxifen. - more of my story here. This is my story, getting though treatment for breast cancer one day, one vlog at a time. Life is good.
  • TAMRAD: A GINECO Randomized Phase II Trial of Everolimus in Combination with Tamoxifen... San Antonio Breast Cancer Symposium 2010 - A discussion with Dr. Thomas Bachelot, France, on TAMRAD: A GINECO Randomized Phase II Trial of Everolimus in Combination with Tamoxifen Versus Tamoxifen Alone in Patients (pts) with Hormone-Receptor Positive, HER2 Negative Metastatic Breast Cancer (MBC) with Prior Exposure to Aromatase Inhibitors (AI).
  • Insidermedicine in 60 - August 26, 2009 From New Haven - According to research in the Journal of the American College of Cardiology, many patients who undergo percutaneous coronary intervention are readmitted. In a study of nearly 300000 patients who underwent PCI, researchers found that about 15% were readmitted within 30 days of discharge. Those who were readmitted were also more likely to die within 30 days than those who were not. From Seattle - According to a study in the journal Cancer Research, tamoxifen may increase the risk of some forms of breast cancer. In a study of over 360 breast cancer survivors, researchers found that those who took tamoxifen for secondary prevention had a 4.4 times higher risk of estrogen receptor-negative contralateral breast cancer. However, the researchers caution that these findings don't substantially change the risk-benefit ratio for tamoxifen. And finally, from Alabama - According to research in the journal Neurology, high diastolic blood pressure may be linked to cognitive problems. In a study of nearly 20000 people, researchers found that in those aged 45 and older, every 10-point increase over 90 mm Hg was associated with a 7% higher risk of cognitive problems. This association was not found with systolic pressure. For Insidermedicine in 60, I'm Dr. Kelly Schweitzer.
  • Mini-Medical School: "A Tale of Two Patients: Pharmacogenomics and Tamoxifen in Breast Cancer" UNC's Mini-Medical School is a community-based lecture series designed to give lay audiences first-hand experience with the science underlying the practice of modern medicine. On March 17, 3 UNC School of Medicine faculty lecturers addressed the topic of personalized medicine. William Irvin Jr., MD, presented "A Tale of Two Patients: The World of Pharmacogenomics and Tamoxifen in Breast Cancer."
  • Breast Density Predicts Tamoxifen Effectiveness - Focus for the Cure Dr. Warren Reuther, III Medical Director of Radiology, Columbia Hospital
  • Breast Cancer: Surgery But No Chemo or Tamoxifen They were pushing HRT to everyone who came to the clinic. I was on hormone therapy for 2 years. Then I got breast cancer. I had mastectomy with removal of lymph nodes. The doctor said, "You must do chemo." I refused and asked for other options. Then I got your contact. I was asked to take tamoxifen, but I refused. I go for routine check up every 3 months for 4 years. Fifth year on, it was every 6-monthly. Everything is alright. Today April 2009, patient is doing very well and happy.
  • Starting Tamoxifen. Or Not: Breast Cancer Vlog #72 More of my story here: . In this episode tips for and reality of getting through radiation well using calendula and aloe. And the Tamoxifen dread continues.
  • Professor Mitch Dowsett - Tamoxifen vs Aromatase Inhibitors Professor Mitch Dowsett, Professor of Biochemical Endocrinology at the Institute of Cancer Research Tamoxifen vs Aromatase Inhibitors and highlights of San Antonio Breast Cancer Symposium Highlights of the San Antonio Breast Cancer Symposium, Aromatase Inhibtors vs Tamoxifen, Survival Benefit, BIG 1-98, Letrozole
  • How to Detox from Chemotherapy (Chemo) and tamoxifen Hippocrates Health Institute Dr. Brian Clement speaks about chemotherapy detox, rebuilding the cells; and that is sometimes but very rarely advisable to have chemo.
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  • Dr.Jay Harness,Tamoxifen And The Side Effects What Is Tamoxifen And What Are The Side Effects? Help us transform healthcare patient advocacy by tapping into the strength of women at
  • Bite-Sized Biochemistry #50 - Gene Expression II (03/04/11) Lecture by Kevin Ahern of Oregon State University discussing Biochemistry Basics in BB 451. See the full course at oregonstate.edu This course can be taken for credit (wherever you live) via OSU's ecampus. For details, see ecampus.oregonstate.edu Download Metabolic Melodies at Related courses include BB 350 - oregonstate.edu BB 450 - oregonstate.edu BB 100 - oregonstate.edu Highlights Gene Expression 2 1. In eukaryotic cells, DNA is wrapped up (coiled up) with basic proteins called histones. Histone sequences are strongly conserved from yeast to humans. 2. Four histones form a core around which DNA is wrapped. This core contains two copies each of histones H2A, H2B, H3, and H4. This core of proteins is called an octamer. 3. The appearance of chromatin (chromatin = DNA + histones) is that of beads on a string, with the octamer wrapped with DNA composing the beads and the DNA strand coated with histone H1 (and H5) composing the string. 4. Histones of the octamer have strong structural similarity to each other. 5. Wrapping of DNA around the histone octamer provides only partial compression of the length of a DNA molecule. Additional compression occurs as a result of coiling of octamer/DNA complexes as well, forming higher order structures. 6. Nuclear hormone receptors, such as the estrogen receptor, have DNA binding domains and ligand binding domains. The binding of the estradiol ligand to the estrogen receptor causes a conformational change ...
  • Pharmacogenomic Testing and Breast Cancer Dr. Hannah Linden, associate professor of medicine at the University of Washington, examines genomic heterogeneity, an emerging and important factor in determining tamoxifen benefit in breast cancer. Dr. Linden reviews recent laboratory and clinical trial evidence regarding tamoxifen metabolism and the impact of CYP2D6 pharacogenomic profiling.
  • Tamoxifen TAMOXIFEN Tamoxifen has rarely caused very serious (possibly fatal) strokes, blood clots in the lungs/legs, and cancer of the uterus. If you are taking tamoxifen to reduce the risk of breast cancer, or if your cancer is limited to the milk ducts (ductal carcinoma in situ-DCIS), then discuss the benefits and risks of taking this medication with your doctor. However, if you are taking tamoxifen to treat breast cancer, then the benefits of taking tamoxifen are greater than the risks of side effects. Seek immediate medical attention if you develop symptoms of a stroke or blood clots in the lungs/legs, such as weakness on one side of the body, slurred speech, sudden vision changes, confusion, shortness of breath, chest pain, or calf pain/swelling. Tell your doctor immediately if you develop symptoms of cancer of the uterus, such as unusual changes in your monthly period (eg, amount or timing of bleeding), unusual vaginal discharge, or pain/pressure below your "belly button" (navel). USES Tamoxifen is used to treat breast cancer that has spread to other parts of the body (metastatic breast cancer), to treat breast cancer in certain patients after surgery and radiation therapy, and to reduce the chances of breast cancer in high-risk patients. This medication can block the growth of breast cancer. It works by interfering with the effects of estrogen in the breast tissue. OTHER USES This section contains uses of this drug that are not listed in the approved professional labeling ...
  • Zinc(II) ion mediates tamoxifen-induced autophagy and cell death in MCF-7 breast cancer cell line From the Springer article: Zinc(II) ion mediates tamoxifen-induced autophagy and cell death in MCF-7 breast cancer cell line by: Hwang, Jung Jin; Kim, Ha Na; Kim, Jean; Cho, Dong-Hyung; Kim, Mi Joung; Kim, Yong-Sook; Kim, Yunha; Park, Sung-Jin; Koh, Jae-Young; Live cell confocal microscopic images (2 minutes/frame) of MCF-7 cells transfected with LC3-GFP, 60-90 minutes after addition of 17 μM tamoxifen in HBSS. Images were obtained from z-series collections (35 z-section images of 1 μm thickness). (AVI 464 kb) Journal: BioMetals Vol. 23 Issue 6 DOI: 10.1007/s10534-010-9346-9 Published: 2010-11-08
  • Insidermedicine In Depth - February 8, 2010 - Paroxetine Taking the antidepressant paroxetine interferes with the life-saving properties of the breast cancer therapy tamoxifen, according to research published in the British Medical Journal. Here is some information about cancer and depression: • An estimated 15 to 25% of cancer patients suffer from depression • Depression associated with cancer can usually be treated with a combination of counseling and medication • Depressed cancer patients should be evaluated by a professional for their risk of suicide Researchers from Sunnybrook Odette Cancer Centre in Toronto and from the Institute for Clinical Evaluative Sciences (ICES) ***yzed the long-term survival rates of nearly 2500 Ontario women aged 66 and older who were treated with tamoxifen for breast cancer between the years 1993 to 2005. These women were also treated with one antidepressant of the SSRI class for some or all of the time they were taking tamoxifen. Overall, about 30% of the women received antidepressant treatment while taking tamoxifen. After adjusting for factors that affect survival rates, including age, women who were taking paroxetine, which is also known under its tradename Paxil, while taking tamoxifen were more likely to die from breast cancer than those who had not taken this drug. The more paroxetine therapy overlapped with tamoxifen therapy, the higher the risk of dying from breast cancer. The authors estimate that using paroxetine for 41% of the duration of tamoxifen therapy would result in 1 ...
  • ASCO 2009: Impact of common antidepressants on tamoxifen effectiveness Dr. Vincent O. Dezentjé - Leiden University Medical Center, Leiden, The Netherlands ASCO press conference: Two studies report differing results about whether the antidepressants, fluoxetine and paroxetine, have an adverse impact on the effectiveness of tamoxifen.
  • Tamoxifen Infomercial
  • San Antonio Breast Cancer Symposium 2008: BIG 1-98: Letrozole vs tamoxifen BIG 1-98: A randomized double-blind phase III study evaluating letrozole and tamoxifen given in sequence as adjuvant endocrine therapy for postmenopausal women with receptor-positive breast cancer. Alan Coates, MD, clinical professor in the School of Public Health at the University of Sydney in Australia, speaking at the 2008 San Antonio Breast Cancer Symposium
  • Discovering Key to Tamoxifen's Effectiveness in Treating Breast Cancer may Mean New Treatments Mayo Clinic researchers have discovered that a chemical known as endoxifen appears to be the primary metabolite responsible for the effectiveness of tamoxifen in treating breast cancer, and that it works against cancer in an entirely unexpected way. Dr. Thomas Spelsberg, Ph.D., a Mayo Clinic molecular biologist addresses the study.
  • MediaPharm - Paxil-Tamoxifen Interaction: What you don't know can kill you How does a common antidepressant increase death from breast cancer? How can you protect yourself from this deadly interaction? Join Dr Robert Savage as he discusses how to safely manage this serious interaction.
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  • Important information for every breast cancer survivor taking tamoxifen Tamoxifen is one of our best cancer fighting drugs. It successfully prevents the return of ER (estrogen receptor) positive breast cancer in two-thirds of women who take it. Now the success rate can be improved even further by DNA Testing and careful management of other drugs that are being taken with tamoxifen. More information at
  • Breast Cancer vlog #75 Tamoxifen Meltdown plus: Millie was right! More of my story here: - This is a make-you-laugh, make-you-cry video if ever there was one. Radiation, Tamoxifen, triathlon, and Millie the poodle.
  • Treating Early Breast Cancer The 10-year follow-up data from the Arimidex, Tamoxifen Alone or in Combination (ATAC) trial continue to show that the adjuvant anastrozole significantly reduces the rate of breast cancer recurrence and secondary primary breast cancer in comparison with tamoxifen in postmenopausal, hormone receptor-positive patients, Dr. Aman Buzdar explains.
  • Tamoxifen Use and Second Breast Cancers - Fred Hutchinson Cancer Research Center Presentation by Christopher Li, Ph.D. from Fred Hutchinson Cancer Reserach Center on his study of long-term Tamoxifen use and the occurance of second breast cancers.
  • Insidermedicine In 60 - July 28, 2011 From California - Fructose consumption may raise risk of heart disease, according to a report published in the Journal of Clinical Endocrinology and Metabolism. Researchers studied nearly 50 adults whose daily calorie consumption was 25% glucose, fructose, or high fructose corn syrup. After two weeks, researchers found that consumption of fructose or fructose corn syrup increased LDL cholesterol, triglycerides and apolipoprotein-B--all risk factors for heart disease. From Oxford - 5 year tamoxifen therapy greatly improves survival for most breast cancer patients, according to a report published in the Lancet. Results of a meta-***ysis covering over 20000 breast cancer patients found that full compliance with a 5 year tamoxifen regimen reduced long term risk of death by at least 33%. And finally, from California - More muscle mass may lower risk of insulin resistance (pre-diabetes), according to a report published in the Journal of Clinical Endocrinology and Metabolism. Studying over 13600 individuals, researchers found that increased muscle mass was linked to better insulin sensitivity and a reduced risk of pre-diabetes
  • Tamoxifen And Blood Clots Dr. James G. Schwade reports on a potential connection between Tamoxifen and blood clots in women.
  • Tamoxifen Efficacy - Focus for the Cure Dr. Elisabeth McKeen, FACP Medical Oncologist, Palm Beach Cancer Institute
  • Breast Cancer: Lumpectomy & Radiation - No Chemo or Tamoxifen Fay decided to go for lumpectomy and all 8 lymph nodes were removed were clean. Doctor said: Stage 1, but must do radiotherapy and chemotherapy. I protested and doctor agreed I go for radiation only. I received 15X radiation. That was 8 years ago, I am well today.

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