- Frequently asked questions about mitochondrial disease, symptoms of mitochondrial disease, and mitochondria. — “About Mitochondrial Disease - Mito FAQ | MitoAction”,
- There is the outer mitochondrial membrane, the intermembrane space (the space between the outer and inner membranes), the inner mitochondrial membrane, the crista space special mitochondrial ribosomes, tRNA, and several copies of the mitochondrial DNA genome. — “Mitochondrion - Wikipedia, the free encyclopedia”,
- Mitochondrial Diseases Mitochondria are intracellular organelles that play a critical role in cellular metabolism. — “Mitochondrial disease: Information from ”,
- Mitochondrial Eve is a person who is a common ancestor to all living humans on a female-only ancestral line. The phrase Mitochondrial Eve refers to the parts of the human cell called mitochondria. — “Mitochondrial Eve - SkepticWiki”,
- In mitochondrial diseases, the mitochondria cannot efficiently turn sugar and oxygen into energy, so the cells do not work correctly. When a child has both autism and a mitochondrial disease, they sometimes have other problems as well,. — “CDC - Mitochondrial Disease, Autism Spectrum Disorders - NCBDDD”, cdc.gov
- A comparison of the mitochondrial DNA of humans from many races and regions suggests that all of these DNA sequences have evolved molecularly from a common ancestor sequence. Although she was named after the Biblical Eve, mitochondrial Eve was not the sole living human female of her day. — “Mitochondrial Eve - Definition”,
- Flowering plants harbor the largest mitochondrial genomes reported so far. angiosperm mitochondrial genomes, even within a species, show a remarkable amount of rearrangement. — “Angiosperm mitochondrial genomes and mutations”, hos.ufl.edu
- Synthesized in mitochondrial matrix. Sorted to matrix or inner membrane. Oxidase assembly Precursors synthesized in cytoplasm with mitochondrial targeting sequence. — “Mitochondrial Disorders”, neuromuscular.wustl.edu
- Our mission is to promote research and education for the diagnosis, treatment and cure of mitochondrial disorders and to provide support to affected individuals and families. TEXT YOUR DONATION TO THE UMDF. You can make a $10 donation to the UMDF simply by texting the word ENERGY to 85944. — “United Mitochondrial Disease Foundation”,
- Definition of mitochondrial in the Online Dictionary. Meaning of mitochondrial. Pronunciation of mitochondrial. Translations of mitochondrial. mitochondrial synonyms, mitochondrial antonyms. Information about mitochondrial in the free online. — “mitochondrial - definition of mitochondrial by the Free”,
- Mitochondrial genetics are the genetics of the DNA contained in mitochondria, eukaryotic cell organelles that generate adenosine triphosphate from pyruvic acid and are hence referred to as the "powerhouses" of the cell. Mitochondrial. — “Mitochondrial genetics - Psychology Wiki”,
- MITOCHONDRIAL DISORDERS. ENERGY PRODUCTION AND FREE RADICALS. This page describes conditions that impair oxidative phosphorylation (oxphos), the process by which mitochondria capture the energy in pyruvate and fatty acids and store it as ATP. — “Mitochondrial disorders”,
- Mitochondrial disorders, also called mitochondrial cytopathies, are a diverse group of diseases caused by damage to small structures found in human cells that are essential in converting food to energy. The result is decreased energy production. — “Mitochondrial Disorders Information on Healthline”,
- Causes and treatments for mitochondrial dysfunction in Chronic Fatigue Syndrome sufferers. — “Health-spy CFS - Mitochondrial Dysfunction”, health-
- Definition of mitochondrial in the Medical Dictionary. mitochondrial explanation. Information about mitochondrial in Free online English dictionary. What is mitochondrial? Meaning of mitochondrial medical term. What does mitochondrial mean?. — “mitochondrial - definition of mitochondrial in the Medical”, medical-
- Read about mitochondrial disease is a group of neuromuscular diseases with symptoms like muscle weakness, heart failure, dementia, deafness, blindness, movement disorders, stroke-like episodes and more. — “Mitochondrial Disease Causes, Symptoms, Diagnosis, and”,
- Mitochondrial myopathy symptoms, causes, diagnosis, and treatment information for Mitochondrial myopathy (Mitochondrial diseases) with alternative diagnoses, full-text book chapters, misdiagnosis, research treatments, prevention, and prognosis. — “Mitochondrial myopathy - ”,
- To provide parents with information, support and access to resources to help them understand Mitochondrial Disease. Our aim is to find a treatment and CURE for our child's mitochondrial disorder. — “Mitochondrial Disorder; Information for Parents”, mitochondrial-disorder-
- What is mitochondrial DNA? Mitochondria are structures within cells that convert the energy from food into a form that cells can use. Although most DNA is packaged in chromosomes within the nucleus, mitochondria also have a small amount of their own DNA. — “Mitochondrial DNA - Genetics Home Reference”, m.nih.gov
- Mitochondrial myopathies have many different faces. As you will read in this booklet, dozens of varieties of mitochondrial diseases have been identified, with a complex array of symptoms. This booklet has been prepared to help you understand the causes of and treatments for mitochondrial myopathies. — “Facts About Mitochondrial Myopathies”,
related videos for mitochondrial
- Evidence for Evolution: Complete Neanderthal mt Genome Update May 2010!!! The initial draft of the Neanderthal nuclear genome has been completed (~3 billion base pairs). It turns out, that people of European and Asian descent inherited a small amount, an average 1% to 4% of their genes, from Neanderthals. See link to Science Article/Video: Initial publication in this Video: Cell, Volume 134, Issue 3, 416-426, 8 August 2008 "A Complete Neandertal Mitochondrial Genome Sequence Determined by High-Throughput Sequencing" (PM me and I will send you the entire article) Evolution vs Creationism Science vs Myths
- Fertility breakthrough for inherited mitochondrial disease (HD) | A film by the Wellcome Trust Scientists at Newcastle University have developed a pioneering technique which enables them for the first time to successfully transfer DNA between two human eggs. The technique has the potential to help prevent the transmission of serious inherited disorders known as mitochondrial diseases. To find out more, visit
- The David P. Campbell Mitochondrial Fellowship Dr. Mary J. Hall Willis talks about her David P. Campbell Fellowship in Mitochondrial Medicine which she served from July 2005 to June 2007 at the University of California, San Diego School of Medicine. Short video extract from Your Story Here Video Editing:
- Mitochondrial Disease & It's Association with Autism 8 minutes of a 40 minute presentation of basic background on Mitochondrial Disease and on its association with Autism or ASD (Autistic Spectrum Disorders) by renown Mitochondrial specialist, Dr Fran Kendall founder of Virtual Medical Practice. Balance of presention may be found on /Lectures.html.
- The Science of Mitochondrial Medicine Vamsi Mootha, MD PhD at Harvard speaks on behalf of MitoAction about the impact of the mitochondria on many common diseases and the aging process.
- A Cure for Mito Elliott Bay Productions produced, directed and edited, "A Cure for Mito," a 6-minute story showcasing the complexities of Mitochondrial Disease and the impact it has on families. This piece was presented at the 2010 Mitochondrial Research Guilds Fundraising Event.
- An Adult Mitochondrial Disease Patient's Spouse Gordon Russell speaks about his wife, Sandra, and their family's experience with mitochondrial disease.
- LIFE SCIENCES | Methods in Enzymology (3) The Mitochondrial Function Series Methods in Enzymology (MIE) is one of the most highly respected publications in the field of biochemistry. In this video, editors John Abelson and Mel Simon talk about the Mitochondrial Function Series. MIE includes volumes containing contributions from more than 200 scientists in this rapidly evolving field, including Editors William S. Allison, Immo E. Scheffler and Anne N. Murphy.
- Regulation of the mitochondrial CoA Acetyl-CoA ratio www.carnitinaofficialsite.it Carnitine carries out a fundamental role in regulating the acyl CoA/CoA and acetyl CoA/CoA ratios Coenzyme A in its free form (CoA) is an essential factor for most metabolic cellular processes. The mitochondrial membrane is however impermeable to CoA, thus the mitochondrial pool cannot be replenished from the cytoplasmic pool and vice versa. Cellular concentrations of CoA depend on how far its acyl-CoA and acetyl-CoA derivatives are respectively converted to acylcarnitine and acetylcarnitine by carnitine and by acylcarnitine transferase enzymes producing free CoA. CoA regulates the activity of the pyruvate dehydrogenase enzyme and of many dehydrogenases of beta-oxidation which in turn controls the production of acetyl-CoA. Acetyl-CoA enters the Krebs cycle resulting in the formation of ATP. By regulating the intracellular availability of CoA carnitine therefore carries out a fundamental role in metabolic processes.
- Living with Mitochondrial Disease What does it mean to live with mitochondrial disease? One in 4000 adults and children have mitochondrial disease ("Mito") and more are being diagnosed each year. Watch the experience of 4 different people whose lives have been changed by a disorder and a disability that affects the powerhouse of the cell. Their disease may be invisible, but their challenges are great. Learn more and make a difference at Produced by Wendy Fine: Producer Nahid Shahabi: Assistant Producer Corey Sheehan: DP Zeen Rachidi: Editor/Lighting Kevin Mee: Sound/Grip Nick Cali: Sound/Grip/ Assist. Editor Evan Warren: Second Camera
- The faces of Mitochondrial Disease Dr. Pam Johnson, a UMDF member, explains her diagnosis and why more federal funding is needed for research into primary mitochondrial disease.
- more mitochondrial ATP
- Children With Mitochondrial Disease Help find a cure
- Living life with Mitochondrial Disease This is about the life of a child living with Mitochondrial Disease. He has this disease, but this disease doesn't have him, it doesn't capture his spirit and who he is!
- Mitochondrial links to genomic instability in aging Understanding why our genomes become more prone to mutations as we age is a key goal of ageing and cancer research. Dr. Dan Gottschling and his colleagues have identified that in budding yeast a loss of DNA and certain proteins in the mitochondria that occurs during ageing causes increase instability of the nuclear genome.
- Mitochondrial Disease: One Child's Battle Eithene Rose was born with Complex IV Mitochondrial Disease. Before birth, her defective mitochondrial function caused multiple birth defects, resulting in VACTERL Association. Eithene's life has been spent in hospitals treating the effects of these birth defects as well as continuing progressive organ dysfunction (also from the mito) throughout her body.
- Mitochondrial Myopathy | Miracle Natural product for mitochondrial myopathy Mitochondrial Myopathy | Miracle Natural product for mitochondrial myopathies. Watch Fox News story Testimony about a Miracle Natural product for mitochondrial myopathy. Univera's products were recently featured in a Fox 10 News segment in Phoenix, Ariz. Sandra Giani Kipness, who suffers from a rare disease called mitochondrial myopathy, recounts how discovering products including Ageless Xtra helped increase her energy and stamina.* Chief Scientific Officer Stephen Cherniske rounds out the segment with more information about Univera. * Univera products are not intended to cure, treat or prevent diseases and should not be considered a substitute for any medication prescribed by your doctor.
- Mitochondrial DNA mitochondrial DNA
- Mitochondrial Functional ***ysis: A new Method and Strategies - Frank Schallenberger, MD Frank Schallenberger, MD speaks about Mitochondrial Functional ***ysis: A new Method for Assessing Anti-Aging Strategies at the 16th annual A4M conference in Orlando, Florida. Enjoy this short DiGiVision clip. Visit /freelectures to see full free lectures and also to purchase many others. Visit to learn more about this conference organizer. Item #A4M081WSatBrk2-3
- New Test Helps Detect Mitochondrial Disease (Copyright © 2010, KTLA-TV, Los Angeles)
- Living with mitochondrial disease Two families living with mitochondrial disease. For more about Jack visit .
- Meet The Afrikan, Mitochondrial Eve Part 1 Meet The Afrikan, Mitochondrial Eve Part
- Who Was Mitochondrial Eve? This video explains the concepts of Mitochondrial Eve and Y-Nuclear Adam, what their relationship to evolution and human lineage is, and how creationists claims about them are just pathetically wrong. Update: More news on the controversy over whether Neanderthals were the same species as humans.
- Mitochondrial Disease Advocacy Speech Providing a voice for persons with mitochondrial disease.
- A young adult with Mitochondrial Disease Lisa Parker looks normal and healthy. Yet in her twenties she was diagnosed with mitochondrial disease and lost her "normal" young adulthood.
- Faces of Mitochondrial Disease - The Swinns Chris and Mary Swinn and their daughter Emily describe what it is like to live with mitochondrial disease.
- Mom & *** Daughter with Mitochondrial Disease Speak Theresa & Brianna Couture, mom and her 15 year old daughter, speak emotionally about trying to live while having mitochondrial disease.
- Re: Cecal Valves & Mitochondrial DNA 1. You are right. I misread the latin. 2. The articles discussed that latent DNA had this possible function on polymorphic traits. The only way that cecal valves could form by latent DNA is if the Italian Wall Lizard had a polymorphic trait for its intestinal structure, which it appears it does not. 3. Genetics have advanced a lot since Mendel's discoveries, but there is no evidence that such a thing happened with the Italian Wall Lizard. 4. The Mitochondrial DNA being identical shows that the Italian Wall Lizards with cecal valves were directed dissented from those 5 breeding pairs and were not the result of cross-breeding. Also this is not evidence for the coding for the cecal valve already existing because that coding would exist in the main double helix, not the Mitochondrial DNA. 5. Adaptation and Evolution are the same thing. They both result from the same process.
- Mitochondrial DNA Variation at Position 16189 and Diabetes Mitochondrial DNA Variation at Position 16189 and Diabetes: Frequency Amongst South Eastern Kenyan Populations Mitochondrial dysfunction plays a critical role in the pathogenesis of insulin resistance and Diabetes Mellitus, and mitochondrial mutations have been reported to be a cause of maternally inherited diabetes and some features of metabolic syndrome. A substitution of thymidine for cytosine (T→C) at nucleotide position 16189C of the mitochondrial genome (mtDNA) may be associated with insulin resistance and type 2 Diabetes Mellitus. An ***ysis of subjects from five Asian countries confirmed an association between the 16189C variant and type 2 Diabetes Mellitus. However, a meta-***ysis of previous research on European subjects did not show an association between the 16189C variant and disease expression. Due to the inconsistency of the results between the studies in Asians and Europeans; we decided to investigate other ethnic populations. DNA was extracted from cheek swab samples collected from the Mijikenda and Taita groups of southeast Kenya. The Hypervariable Region I of the mtDNA, where the mutation is found, was sequenced. The mutation is found at low frequencies in these Kenyan populations, 8.61% in the Taita sample and 9.62% in the Mijikenda sample. In contrast, previous studies indicated frequencies of 31.0% in Asian and 9.2% in European samples. Ethnic differences among populations may underlie risk association in a complex disease such as diabetes because ...
- ☥MITOCHONDRIAL DNA☥ III ~ Necessary Production Nu Edutainment Films Mitochondria (illustration) are structures within cells that convert the energy from food into a form that cells can use. Each cell contains hundreds to thousands of mitochondria, which are located in the fluid that surrounds the nucleus (the cytoplasm). Mitochondria produce energy through a process called oxidative phosphorylation. This process uses oxygen and simple sugars to create adenosine triphosphate (ATP), the cell's main energy source. A set of enzyme complexes, designated as complexes IV, carry out oxidative phosphorylation within mitochondria. In addition to energy production, mitochondria play a role in several other cellular activities. For example, mitochondria help regulate the self-destruction of cells (apoptosis). They are also necessary for the production of substances such as cholesterol and heme (a component of hemoglobin, the molecule that carries oxygen in the blood). Mitochondrial DNA contains 37 genes, all of which are essential for normal mitochondrial function. Thir*** of these genes provide instructions for making enzymes involved in oxidative phosphorylation. The remaining genes provide instructions for making molecules called transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), which are chemical cousins of DNA. These types of RNA help assemble protein building blocks (amino acids) into functioning proteins.
- The Meaning of Mitochondrial Disease What does it mean to be living with Mitochondrial Disease? MitoAction is a Boston based nonprofit dedicated to improving quality of life for the thousands of adults and children affected by this devestating disease. We need your help! Your gifts directly improve patient care through support and collaborative education. Learn more at
- Mitochondrial Disease This is a montage type of video to educate and raise awareness of mitochondrial disease. Included are just some of the faces of those affected by mitochondrial disease. There are thousands more out there...all of them need our help! To learn more about how you can make a difference and be a part of finding a cure please visit the United Mitochondrial Disease Foundation at NO COPYRIGHT INFRINGEMENT INTENDED.
- Mitochondrial: Our Bodies Power Plants A general overview of Mitochondrial Disorders by renown Mitochondrial specialist, Dr Fran Kendall founder of Virtual Medical Practice, to Georgia State School Nurses. Balance of presenation is located at
- Common binding site of mitochondrial carriers Models of the ornithine carrier, aspartate/glutamate carrier, carnitine/acetylcarnitine carrier, and oxoglutarate transporter, showing their predicted binding ite, and substrates docking to them. Robinson, AJ & Kunji, ER (2006). Mitochondrial carriers in the cytoplasmic state have a common substrate binding site. Proc Natl Acad Sci USA 103, 2617-22.
- Visualization of chimp and human mitochondrial DNA The recent publication of the complete chimp genome, marked by a celebratory issue of the journal Nature, tells us that humans and chimps share 96 percent of the same genetic material. This number is hard to comprehend, what exactly does it means to say that we share 96% of our DNA with our closest living cousins? Directly examining the DNA it self does not help. For example, consider the first 100 base pairs of the chimps mitochondrial DNA: gtttatgtagcttaccccctcaaagcaatacactgaaaatgtttcgacgggtttacatcaccccataaacaaacaggtttggtcctagcctttctattag... and the first 100 base pairs of the Humans mitochondrial DNA: gatcacaggtctatcaccctattaaccactcacgggagctctccatgcatttggtattttcgtctggggggtgtgcacgcgatagcattgcgagacgctg... It is very difficult to gauge similarity, and the full genome for both human and chimp is actually about 3 billion base pairs long! We have built a simple tool to allow people to visualize and understand the similarity/dissimilarity of DNA sequences. While this work is currently unpublished and still ongoing, we have released a video relating to human and chimp DNA to coincide with the publication of the complete chimp genome. High res version available at www.cs.ucr.edu/~eamonn/DNA/
- Mitochondrial DNA This animated tutorial is the third in a series of five videos exploring molecular genealogy. In this video you will discover how mitochondrial DNA can be a rich source of information for deep ancestry, going back thousands of years.
- MEDomics MitoDx: New Test for Mitochondrial Diseases (© MMX, CBS Broadcasting Inc. ) MEDomics, LLC announces an innovative test for early diagnosis of mitochondrial diseases, a group of disorders that can result in neurological dysfunction, muscle weakness, gastrointestinal symptoms, migraine headaches, blindness, deafness, and diabetes. The MEDomics mitochondrial genome test, MitoDx™, uses revolutionary NextGen sequencing technology to detect all mutations in any of the 37 mitochondrial DNA genes. The MEDomics team of experts provides interpretation of the functional significance of detected mutations. This comprehensive test offers exceptionally high diagnostic utility for suspected mitochondrial disease, enabling potentially lifesaving therapy and accurate risk counseling. Disease from mutations in mitochondrial DNA is now thought to be common in both adults and children. In childhood, mitochondrial disease is more common than muscular dystrophy or cancer. Most mitochondrial disease may go undiagnosed because a primary care physician does not suspect the disease or because the causative mutation is missed by current methods. To my knowledge, MEDomics is the first laboratory to offer a whole genome clinical diagnostic test utilizing the powerful NextGen sequencing technique says Steve S Sommer, MD, PhD, Founder and President of MEDomics. Mitochondria are the power plants of the cell, providing energy for cellular processes, including growth, and metabolism. Mutations in mitochondrial genes may decrease energy production and affect multiple organs. Since ...
- "Mitochondrial Eve & the 3 'Daughters' of Noah" Dr Rob Carter How is recent genetic research confirming the reality of the Bible accounts of the Creation, the Flood and the Tower of Babel? Full 37 min talk available on DVD at the CMI webstore — /store
- A battle with Mitochondrial Disease Tyler's Carepage Video Tyler's battle with Mitochondrial Disease.
- Mitochondrial Disease: Breakthroughs and Interventions - M. Nicholas Martin, MD, ABFP, ABAAM M. Nicholas Martin, MD, ABFP, ABAAM speaks on Mitochondrial Disease: Breakthroughs and Interventions at the 16th annual A4M conference in Orlando, Florida. Enjoy this short DiGiVision clip. Visit /freelectures to see full free lectures and also to purchase many others. Visit to learn more about this conference organizer. Item #A4M081WSatBrk2-1
Blogs & Forum
blogs and forums about mitochondrial
“A Health, Nutrition, and Alternative Medicine Blog. Friday, June 26, 2009. New test for mitochondrial disease. New research has found a potential way to evaluate the severity of mitochondrial diseases, and give doctors insight into if and how their treatments are working”
— Vitamin Stuff Blog,
“Specific decrease of mitochondrial thermogenic capacity in brown adipose tissue of obese SHR/N-cp rats The metabolic properties of brown adipose tissue (BAT), liver, and skeletal muscles were compared in lean and obese diabetic SHR/N-cp”
— mitochondrial thermogenic capacity in brown adipose tissue,
“N-tert-butyl hydroxylamine, a mitochondrial antioxidant, protects human retinal pigment epithelial cells from iron overload: relevance to macular degeneration. [ FASEB J. 2007] Tags: J Neurochem. Posted in Mitochondrial Dysfunction | No Comments " Search Blog:”
— Mitochondrial Dysfunction " Blog,
“MitoAction, since its humble beginnings in 2005, has grown to a global non-profit organization with a trustworthy and dependable reputation. MitoAction will continue to help patients and families living with mitochondrial disease for many years Hundreds participate in the online forum”
— A Renewed Commitment & A Fresh Look for MitoAction | MitoAction,
“Uranium, Mercury, Cancer & Diabetes Hyperinsulinemia may promote mammary carcinogenesis. Insulin resistance has been linked to an increased risk of”
— DNA & Mitochondrial Time Bombs | Dr. Mark's Blog,
“Selective sweeps limit mitochondrial diversity in animals. An exciting mitochondrial diversity within species (eg Bazin et al 2006 Science 312:570, see also”
— The Barcode of Life blog " Blog Archive " Selective sweeps, phe.rockefeller.edu
“New Blog: Mitochondrial Vertigo. The Frames /sing is – relatively Mitochondrial Vertigo: The New Blog. Amazing, Surreal Film of the Thai Protest Conflict”
— New Blog: Mitochondrial Vertigo | Frames /sing,
“This blog details recent news in Jacks mitochondrial disease research, treatment, mitochondrial medication, and mitochonria specialists around Australia & the world searching for a cure”
— Mitochondrial disease Blog, mitochondrial-disorder-
“What is mitochondrial disease? How often does it occur in individuals with ASD? is a new weekly feature on our blog to address the desire for scientific understanding in our community”
— What is mitochondrial disease? How often does it occur in,