filopodia

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Examples
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  • Filopodia are thin, actin-rich plasma-membrane protrusions that function as antennae for cells to probe their environment. Consequently, filopodia have an important role in cell migration, neurite outgrowth and wound healing and serve as precursors for dendritic spines in neurons. — “Filopodia: molecular architecture and cellular functions”,
  • Filopodia are linked to cell migration, where their role is presumably to sense the surrounding extracellular environment, providing spatial information to direct movement. Protrusion of filopodia appears to be tightly regulated by the Rho. — “TNF{alpha} induces sequential activation of Cdc42- and p38”,
  • VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia Double staining for endothelial markers and nuclei revealed that the extension of long filopodia is largely restricted to the tip cells. — “VEGF guides angiogenic sprouting utilizing endothelial tip”, m.nih.gov
  • [LOCATION] You are located in menu-tree (+1) for the word-cloud of "filopodia" [VIEW] The number below that words indicates the max. amount of logical connections to "filopodia", that are available. — “filopodia”, w9
  • Filopodia that extend from neuronal growth cones sample the environment for differentially within filopodia on one side of the growth cone. — “Filopodial Calcium Transients Promote Substrate-Dependent”, bilbo.bio.purdue.edu
  • such as filopodia and retraction fibers of fibroblast cells (Fig. 1) HEK 293 cells that exhibited abundant filopodia and retraction. fibers revealed that viral. — “Actin- and myosin-driven movement of viruses along filopodia”, med.yale.edu
  • However, when we investigated the role of mDia2 formin by functional approaches, we unexpectedly found that it is essential, not only for filopodia, but also for lamellipodia. Moreover, functions of mDia2 in lamellipodia and filopodia appeared intimately linked. — “PLoS Biology: Novel Roles of Formin mDia2 in Lamellipodia and”,
  • These filopodia are filled with bundled actin filaments which were born in and converged from the lamellipodial network. A cell migrates along a surface by extending filopodia at the leading edge. — “Filopodia - Wikipedia, the free encyclopedia”,
  • filopodia in expressing cells. Using time-lapse imaging and electron microscopy of IRSp53 Actin filaments in the I-BAR-induced filopodia, in contrast to normal filopodia, do not have a uniform length, are less. — “Coordination of Membrane and Actin Cytoskeleton Dynamics”, bio.upenn.edu
  • While there are several mathematical models of filopodia initiation and growth, testing the capacity of these theoretical models Filopodia are also involved in cancer progression, as many filopodial proteins are known. — “BioMed Central | Full text | Robust patterns in the”,
  • To understand growth cone pathfinding, it will be necessary to understand the molecules and mechanisms that control the formation of lamellipodia and filopodia in the growth cone. but did not reduce formation of lamellipodia and filopodia (Fig. 4). — “The Actin-Binding Protein UNC-115/abLIM Controls Formation of”,
  • The filopodia are slender cytoplasmic projections, similar to lamellipodia, which extend from the leading edge of migrating cells. They contain actin filaments cross-linked into bundles by actin-binding proteins, e.g. fimbrin (Hanein et al, 1997. — “Filopodia - Psychology Wiki”,
  • filopodia ( ′filə′pōdēə ) ( invertebrate zoology ) Filamentous pseudopodia. These filopodia are filled with bundled actin filaments which were born in and converged from the lamellipodial network. — “Filopodia: Definition from ”,
  • Synapse Formation: Are Dendritic Filopodia Essential? What, When, and Where are Dendritic Filopodia?      Dendritic filopodia are small cytoplasmic projections containing filamentous Factin bundles which protrude from the. — “Project Page Group 1 - Course NEUR 0193: Great Controversies”, wiki.brown.edu
  • Filopodia are commonly found at the free front of migratory tissue sheets and are prominent in neurite growth cones or individual cells such as fibroblasts. Contact differences between substrates or cell types influences the number of protruding filopodia [9]. — “The Manual of Cellular and Molecular Function: Filopodia”,
  • (Figure 1, arrows, Video 1) previously thought to be the upper limit for filopodia length in α1-RFP was clearly localized to filopodia when the cells were spreading on its. — “Integrin-containing Filopodia”,
  • Three Functionally Distinct Adhesions in Filopodia: Shaft Adhesions Control Lamellar Extension Adhesions were detected in individual filopodia of sensory growth cones using optical recordings, adhesion markers, and electron microscopy. — “Three Functionally Distinct Adhesions in Filopodia: Shaft”,
  • Filopodia are rod-like cell surface projections filled with bundles of parallel actin filaments. Lamellipodia, filopodia and membrane ruffles are essential for cell motility, the organization of membrane domains, phagocytosis and the development of substrate adhesions. — “filopodia - - Human pathology - Photos - pictures”,
  • strated that these dendritic filopodia are highly dynamic struc- tures, capable of exploring their local cellular environment and It is thought that if dendritic filopodia function as initial bridges. — “Article”, pt.med.gunma-u.ac.jp
  • Having an extremely asymmetric geometry, filopodia require robust cellular mechanisms to In conventional filopodia at the leading edge of migrating cells this role is played by a. — “PLoS ONE: Coordination of Membrane and Actin Cytoskeleton”,

Images
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  • We count the filopodia of 30 cells at various positions in the chip and compare the increase in filopodia in the front side DNf and in the rear side DNr The results is
  • If the slide opens in your browser select File > Save As to save it Click on image to view larger version Figure 2 Dendritic spine elongation and new filopodia formation are induced by RGD containing peptide in 14 DIV hippocampal neurons A C Confocal images of GFP labeled 14 DIV mouse
  • Genus Thin test spherical to elongate ellipsoid pseudostome terminal many filopodia branching and anastomosing many species Kudo 1966 Species
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  • and is called growth cone It consists of a central area c region filopodia and lamellopodia and is highly motile Shaped like a hand it feels its way trough the embryo laying down the axon in its wake Faced with different signals the growth cone will adapt its growth direction away from or towards a signal source or it may simply collapse upon contact with a
  • Genus Thin test spherical to elongate ellipsoid pseudostome terminal many filopodia branching and anastomosing many species Kudo 1966 Species
  • Click on image to view larger version Figure 8 Abl overexpression and Bcr Abl mi***pression alter filopodia and lamellipodia A E Stills movies of amnioserosa in living embryos expressing moesin GFP Mi***pression driven
  • Genus Thin test spherical to elongate ellipsoid pseudostome terminal many filopodia branching and anastomosing many species Kudo 1966 Species
  • growth cone the axon s tip controls the path taken by the growing axon though 1 extending filopodia and 2 increasing its surface area by fusion of intracellular vesicles Diffusible long short range cues attractive repulsive bind to receptors in the axon Neuronal survival synapse formation and refinement Junctions between nerve cells and muscle cells in
  • Genus Thin test spherical to elongate ellipsoid pseudostome terminal many filopodia branching and anastomosing many species Kudo 1966 Species
  • A cultured sensory neuron extending a growth cone with long thin filopodia photo by Ken Balazovich
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  • Genus Thin test spherical to elongate ellipsoid pseudostome terminal many filopodia branching and anastomosing many species Kudo 1966 Species
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  • Uninfected EPEC infected
  • filopodia are thought to trigger the morphological change of dendritic protrusion to spines Differentiation of presynaptic boutons might also be triggered by these axo dendritic contacts Figure 2 Structures syndecan 2 EphB receptor and ephrin B and their putative molecular interactions synapses See text for details
  • 成長円錐が見られる スケールバーは 10 オm B 10 5M LPA でcollapse に陥った成長円錐 突起先端のfilopodia lamellipodia は消失している 図2 LPAの growth cone collapse 活性 胎生7日目ニワトリから摘出した脊髄背側神経核 網膜 腰部交感神経核の細胞は何れも同程度の濃度のLPAで
  • Image showing growth cone sending filopodia toward magnetic nanotubes and making contact with them Microscopic observations showed filopodia
  • figure16 47 jpg 06 Feb 2009 20 06 67K figure16 86 jpg 06 Feb 2009 20 07 51K filopodia jpg 20 Feb 2003 21 04 84K focaladh fluor jpg 10 Feb 2005 19 44 57K
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  • Domain structure of IRSp53 and sequence alignment of IMD and BAR domains A Schematic representation of the domain organisation of IRSp53 Vertical bars in grey are spaced by 100 residues
  • one hour after stimulation This is consistent with the idea that filopodia may mature directly into dendritic spines once they are stabilized by synaptic contact Ziv and Smith 1996 Figure 2 Models of morphological plasticity accompanying LTP Drawings indicate the changes in synaptic contacts before 5 30 min after early and 60 120 min after late LTP induction
  • Genus Thin test spherical to elongate ellipsoid pseudostome terminal many filopodia branching and anastomosing many species Kudo 1966 Species
  • Figure 4 The Q1 growth cone exhibits a strong affinity for filopodia of its contralateral homolog In this time series both Q1 neurons in a single segment were labeled with
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  • Genus Thin test spherical to elongate ellipsoid pseudostome terminal many filopodia branching and anastomosing many species Kudo 1966 Species
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  • Fig 3 A and B show hemocytes with their numerous filopodia as part of an encapsulating structure Besides the filopodia F the nucleous N C representative of hemocytes at the
  • filopodia2
  • expanded in REGENLABPRP showing branching and filopodia x5000 Olympus® inverted microscope Other adjacent cells showed features of cell ruffling Note nucleus lamellopodium and RER
  • EPEC pedestal on intestinal
  • shows similar image as in c The bags of virus arrows are seen exiting from the cell filopodia filopodia Lee and Ng Journal of Nanobiotechnology 2004 2 6 doi 10 1186 1477 3155 2 6 Download authors original image
  • single proteins belonging to the adhesion complex with a fluorescent probe The adhesion sites are initiated under lamellipodia and filopodia as focal complexes Fig 19 Focal complexes can either form and dissolve with a lifetime of around 1 2mins or can persist and differentiate into larger focal adhesions Fig 19 Examples
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  • L pictus midgastrula top and late gastrula bottom Note the filopodia extended by secondary mesenchyme cells SMCs arrow Images by

Videos
related videos for filopodia

  • Ari Helenius (ETH Zurich) Part 3: Open Sesame: Cell Entry and Vaccinia Virus Part 3 focuses on a single virus, the Vaccinia virus, as a model for cell binding, signaling and endocytosis. Fluorescently labeled Vaccinia viruses bind to and surf along host cell filopodia. Helenius lab members noticed that when Vaccinia, unlike other viruses, reached the surface of the cell body it caused the plasma membrane to form blebs. Further experiments showed that the virus tricks the cell into thinking it is apoptotic debris. This induces blebbing and subsequent uptake of the virus by macropinocytosis. Additionally, automated high throughput siRNA screening was used to screen a large number of infected cells for host genes required for Vaccinia virus uptake. ***ysis of the genes identified allowed host factors and processes critical to viral infection to be identified. Expansion of this technique may provide a new source of information on pathogen-host interactions. See more at
  • Actin-rich filopodia Time-lapse widefield micrograph of a C6 glioma cell expressing F-Tractin-GFP to visualize actin filaments. The movie plays at 200X real time.
  • Neurons with inhibited SrGAP2 function Tracking and Segmentation results from an experiment where SrGAP2 gene functions are inhibited. Image contrast has been enhanced for visibility. The original video appears in the upper left. In the upper right, each neuron has been marked with a unique color by our algorithm. In the lower left, each neurite is individually marked with a different color. In the lower right, detected filopodia are marked in red.
  • Ari Helenius Part 3: Open Sesame: Cell Entry and Vaccinia Virus with English Subtitles Part 3 focuses on a single virus, the Vaccinia virus, as a model for cell binding, signaling and endocytosis. Fluorescently labeled Vaccinia viruses bind to and surf along host cell filopodia. Helenius lab members noticed that when Vaccinia, unlike other viruses, reached the surface of the cell body it caused the plasma membrane to form blebs. Further experiments showed that the virus tricks the cell into thinking it is apoptotic debris. This induces blebbing and subsequent uptake of the virus by macropinocytosis. Additionally, automated high throughput siRNA screening was used to screen a large number of infected cells for host genes required for Vaccinia virus uptake. ***ysis of the genes identified allowed host factors and processes critical to viral infection to be identified. Expansion of this technique may provide a new source of information on pathogen-host interactions.
  • a neuron growthcone A 3D animation of a neuron growthcone. It shows the movement of the lamellipodium and filopodia.
  • Newly Discovered Human Brain Genes Are Bad News for Evolution The Chimp-Human 1% Difference: A Useful Lie, 2007 - SsrGAP2 is involved in neuronal migration.[3] A shortened version of this protein allows neurons to migrate faster. This gene is one of the 23 genes that is duplicated in humans but not in other primates.[4] Now for Science Fiction: This protein has been duplicated twice in the human genome in the past 3.4 million years, once 3.4 million years ago and once 2.4 mya. The 2.4 mya duplication resulted in a shortened version that 100% of humans possess. This shortened version allows faster migration of neurons by interfering with filopodia production. Researchers speculate that this may allow humans to build a thicker cerebral cortex.[5]
  • Growth cone guidance by an attractive surface (NGF).mov In this video a DRG growth cone turns after touching an NGF-coated bead. Microtubules and organelles rapidly flow toward the contact point with the bead.
  • Filopodia probes precede ameboid cell motility Source: Simon Moore, Department of Biological Sciences, Columbia University, New York, USA. 10x real-time differential interference contrast video of a mouse spinal commissural neuron axon extending on a polylysine coated glass coverslip. Filopodia extend before the whole cell moves.
  • Filopodia Sprout from Dendrite after Glutamate Spritz Please visit the Smithlab web site (smithlab.stanford.edu) for more information about this movie.
  • Treadmilling Macrophage A time-lapse video of a macrophage (immune cell) biding its time while waiting for an anti-body (IgG) trigger. Internal vesicle transport and filopodia extensions and retractions are clearly visible. (search it on Wiki)
  • Growth cone guidance by an adhesive substrate In this video a DRG growth cone crosses from a fibronectin to a laminin substrate. Filopodial contact with laminin leads the way.
  • Filopodia dynamics Source: Hu Xian, Edna, Mechanobiology Institute, Singapore. CV-1 cells grown on glass coverslips were imaged live using API Delta Vision (100x) for 2min. The dynamic behavior of filopodia such as extension, lateral movement, fusion and retraction can be observed. For more information on this research topic, please visit Sheetz Lab: www.columbia.edu
  • Sema3A treatment small.wmv Growth cone collapse and axon retraction: Embyronic day 10 chicken sensory axons treated at the beginning of the video with semaphorin 3A (Sema3A). 30 min video, 1 min interframe interval. Sema3A induces growth cone collapse, the loss of lamellipodia and filopodia, followed by retraction of the axon tip.
  • neurite outgrowth Growth of axons in the brain
  • B16F1 with GFP fascin and GFP tubulin A B16F1 mouse melanoma cell transfected with GFP-fascin and GFP-tubulin. From Joseph M. Schober, Southern Illinois University Edwardsville, School of Pharmacy.
  • Movie S1 This video shows the response of a growth cone to the localized irradiation of a second nearby axonal shaft. The growth cone can be seen to extend multiple filopodia toward the damage site on the irradiated axon, some of which contact the axon. The filopodia subsequently regress. Field of view: 40 µm x 40 µm. Time lapse movies with time in seconds indicated on the left top of the screen. Minus sign (-) indicates frames captured before the laser exposure. At time "000s", the axon was injured at the position indicated by marker "x" and the frame was paused for 2 seconds for better viewing.. This research was published in the journal Interface in the paper: 'Neuronal growth cones respond to laser-induced axonal damage' by Tao Wu, Samarendra Mohanty, Veronica Gomez-Godinez, Linda Z. Shi, Lih-Huei Liaw, Jill Miotke, Ronald L. Meyer, and Michael W. Berns. The doi link for the article is
  • Patterns of stripes form and align under the influence of signal noise. A simulation in a 20x20 hexagonally packed array of cells with signalling at a range of 2 cells. Ns=0.1, T=9. This research was published in the journal Royal Society Interface: The importance of structured noise in the generation of self-organizing tissue patterns through contact-mediated cell--cell signalling by Michael Cohen, Buzz Baum, and Mark Miodownik. The doi link for the article is Active cells are shown in black. Patterns of stripes form and then align themselves with the boundaries where there is no inhibitory signal (see Figure 6a).
  • Dynamics of Dendritic Filopodia in Hippocampal Slice Please visit the Smithlab web site (smithlab.stanford.edu) for more information about this movie.
  • A Tip Cell During Blood Vessel Formation A 3D view of the leading endothelial cell (tip cell) in a developing blood vessel (isolectionB4-labelled, green). This particular cell possesses numerous thin projections called 'filopodia'. These filopodia are rich in actin filaments (phalloidin-labelled, red). Filopodia explore extracellular cues and are important for the migration of endothelial cells during the formation of new blood vessels, a process known as angiogenesis. Scale: 49.2X49.2X15 um. Franco et al., Developmental Cell 15(3), 448-461.
  • Cellular Recognition | Cell Dance 2010, 1st Place in Video U. Serdar Tulu, Ph.D., of Duke University, for his film, "Cellular Recognition," showing the dynamics of the slender cytoplasmic projections, filopodia, during the development of a fruit fly (Drosphila melanogaster) embryo. Source: American Society for Cell Biology
  • Pseudopod Extension in Nutrient Poor Conditions Visualisation of emergence of pseudopod extension in multi particle model of chemotaxis mediated migration. Local method of dynamic range enhancement is used to visualise the concentration and diffusion of paracrine attractant. In the later stage of the recording, the diffusion rate of the attractant is decreased and the extensions automatically retract into the main body.
  • Neurons with inhibited SrGAP2 function Tracking and Segmentation results from an experiment where SrGAP2 gene functions are inhibited. Image contrast has been enhanced for visibility. The original video appears in the upper left. In the upper right, each neuron has been marked with a unique color by our algorithm. In the lower left, each neurite is individually marked with a different color. In the lower right, detected filopodia are marked in red.
  • Dynamics of Dendritic Filopodia in Hippocampal Slice Please visit the Smithlab web site (smithlab.stanford.edu) for more information about this movie.
  • Growth cone filopodia The cell body is on the right and the advancing tip of the axon is on the left. Notice the numerous filopodia emanating from the advancing tip (known as a growth cone) and their dynamic behavior. Timestamp is hh:mm:ss
  • Neuronal Precursors, chain migration of Neuronal precursors born in the subventricular zone (SVZ) of the neonatal and adult rodent brain migrate 3--8 mm from the walls of the lateral ventricle into the olfactory bulb. This tangentially oriented migration occurs without the guidance of radial glia or axonal processes. The cells move closely associated, forming elongated aggregates called chains, which are ensheathed by astrocytes. We have developed a culture system in which postnatal mouse SVZ neuronal precursors assemble into chains with ultrastructural and immunocytochemical characteristics equivalent to those in vivo but without the astrocytic sheath. Time-lapse videomicrography revealed that individual cells migrate along the chains very rapidly (~122 µm/hr) in both directions. Periods of cell body translocation were interspersed with stationary periods. This saltatory behavior was similar to radial glia--guided migration but ~4 times faster. Neuronal precursors isolated from embryonic cortical ventricular zone or cerebellar external granule layer did not form chains under these conditions, suggesting that chain migration is characteristic of SVZ precursors. This study directly demonstrates that SVZ neuronal precursors migrate along each other without the assistance of astrocytes or other cell types.
  • Filo transition from patches colored.avi Emergence of filopodia from axonal actin patches: Embryonic day 7 chicken sensory axon transfected with eYFP-actin imaged at 6 sec interframe intervals. Note the formation of axonal actin patches, reflected by localized changes in color from blue to red/yellow/white. Also note that finger-like protrusions termed filopodia emerge from the axonal actin patches.
  • Neurons. Brain Cells WWW.GOODNEWS.WS goodnews.ws Our major interest is in actin dynamics in dendritic spines, shown in the top set of movies. Recordings of actin dynamics in growth cones of developing neurons and in non-neuronal cells are shown further down this page. Unless otherwise stated this data is taken from Fisher et al. 1998 Neuron 20 - ACTIN DYNAMICS IN DENDRITIC SPINES - A neuron from rat hippocampus that had been transfected to express GFP-actin and maintained in cell culture for 4 weeks until it had developed dendritic spines in which actin accumulates at high concentrations. The bright fluorescence at top left is part of the cell body where actin is synthesized. The dendritic spines are the bright dots on the dendrites (which extend to the right of the cell body). - The same neuron as in the above figure but presented at two magnifications: first low magnification to show the cell body and dendrites, then zoomed to show a limited section of dendrites. Notice the enormous number of spines on the dendrites of these neurons each marking the site of an excitatory synapse, and their rapid actin-based motility which over this time-scale consists of changes in spine shape (not spine number). - Taken from a recording of another neuron from a different culture, this higher magnification video sequence shows the nature of actin dynamics in dendritic spines in detail. Notice the motile actin-rich protrusions extending from the head of the spine. Their rapid movements occur even though most of them are ...
  • Pseudopod Extension and Retraction Visualisation of the emergence of chemotaxis mediated pseudopod extension and retraction. Left side shows collective particle behaviour and right side shows concentration of paracrine attractant.
  • Fine grained pattern optimisation in a large patterning field. A simulation in a 50x50 hexagonally packed array of cells. Ns=0.1, T=1. This research was published in the journal Royal Society Interface: The importance of structured noise in the generation of self-organizing tissue patterns through contact-mediated cell--cell signalling by Michael Cohen, Buzz Baum, and Mark Miodownik. The doi link for the article is Cells are colour coded according to the key in Figure 4g. Zones of optimised packing form and gradually expand over time (see Figure 4b).
  • Duke Researchers Explore the Sense of Touch Filopodia are narrow spikes on cells, and function as antennae for the cells to probe their environment. Researchers at Duke Medicine, including Asako Tsubouchi, PhD, and Dan Tracey, PhD, are studying filopodia in fruit fly cells to learn more about the sense of touch. This video illustrates the dynamic nature of filopodia, which can form, grow, or disappear in a matter of minutes.
  • Neurons with inhibited NET function Tracking and Segmentation results from an experiment where NET gene functions are inhibited. Image contrast has been enhanced for visibility. The original video appears in the upper left. In the upper right, each neuron has been marked with a unique color by our algorithm. In the lower left, each neurite is individually marked with a different color by our algorithm. In the lower right, detected filopodia are marked in red.
  • Single molecules of M1 receptior on plasma mebrane of CHO cell Submitted to the Andor Insight Awards 2010 - Courtesy of Dr Gregory Mashanov at National Institute for Medical Research, London, United Kingdom G-protein--coupled receptors (GPCRs) are the largest family of transmembrane proteins in the human genome. They play an important role in signal transduction in brain and other tissues. We have used total internal reflection fluorescence microscopy (TIRFM) in living CHO cells to visualize thousands of individual molecules of GPCR, the M1 muscarinic acetylcholine receptor, labelled with florescent ligand Cy3B--telenzepine. Presented video shows M1 molecules moving on cell body and filopodia membranes. Automatic tracking enables us to conclude that M1 molecules undergo unrestricted 2-D diffusion on plasma membrane and pseudo 1-D diffusion on filopodia membrane. This movie was taken using an iXon EMCCD Camera -
  • GC phase.mpg Growth cone dynamics: Embyronic day 10 chicken sensory axon and growth cone imaged using phase contrast optics (100x) and 10 sec interframe interval. Note the growth cone at the tip of the axon. The growth cone exhibits protrusion of lamellipipodia and filopodia, veil and finger like projections respectively. The axon shaft is in contrast much less dynamic.
  • Keratinocyte cell movements Keratinocytes were cultured in a 35mm dish and imaged using a DeltaVision CORE microscope, equipped with an incubator and carbon dioxide mixer. The imaging technique used was Differential Interference Contrast (DIC) microscopy. Time lapse images were acquired every 1 second over a period of 10 minutes. The cells are adhered to the bottom of the culture dish and dynamic movements can be seen within the cells and at the periphery as the cells migrate. Lamellipodia and filopodia can easily be observed.
  • Amoebas Here two amoebas search for food by extending actin-based projections called filopodia. The amoeba on the left shows some spectacular branching filopodia as it hunts for food and substrate. Notice also, especially on the right amoeba, the highly dynamic internal flow of material (vesicles and organelles), caused by the flow of the actin cytoskeleton. I found these in a pond water sample from southern California. They are both moving a piece of pond debris. Images taken at 20X in bright-field on a Nikon Te2000 Microscope.
  • Researchers identify critical gene for brain development, mental retardation Researchers at the University of North Carolina at Chapel Hill School of Medicine have now discovered that establishing the neural wiring necessary to function normally depends on the ability of neurons to make finger-like projections of their membrane called filopodia.
  • DIC microscopy of a B16F1 mouse melanoma cell A mouse melanoma cell recorded for 12 minutes using differential interference contrast (DIC) microscopy. The protrusive cell front consists of a broad lamellipodium with numerous filopodia. Note rapid retraction of the cell tail. Video created by JM Schober, Southern Illinois University Edwardsville, School of Pharmacy.
  • Movie S1 Video recording of a probe particle moved with the help of the laser trap through the PCM towards the cell surface and back. Filopodia-like protrusions can be seen in the vicinity of the surface. This research was published in the Journal of the Royal Society Interface in the paper: 'High-resolution microrheology in the pericellular matrix of prostate cancer cells' by Nadja Nijenhuis, Daisuke Mizuno, Jos AE Spaan and Christoph F. Schmidt. The doi link for the article is
  • Spritz 1 zoom A.mov Local application of the neurotransmitter glutamate causes filopodia sprout from the dendrite of a cultured hippocampal neuron (Smith and Jahr, 1992).
  • Neurons with inhibited MAP2K7 function Tracking and Segmentation results from an experiment where MAP2K7 gene functions are inhibited. Image contrast has been enhanced for visibility. The original video appears in the upper left. In the upper right, each neuron has been marked with a unique color by our algorithm. In the lower left, each neurite is individually marked with a different color. In the lower right, detected filopodia are marked in red.

Blogs & Forum
blogs and forums about filopodia

  • “Weather Underground provides weather information for worldwide locations, including current conditions, hourly forecasts, radar and satellite maps. Specialized weather products include severe weather alerts, hurricane tracking, ski and sports”
    — Wunder Blog : Weather Underground,

  • “Official Blog of Target Health Inc. Home. About Us. Authors. Share This Blog. Share scientists found one of many finger-like filopodia, or spines, that reach out from one”
    — Capturing the Birth of a Synapse : Target Health Global,

  • “Does the fusion protein work as a competitive inhibitor? If so, what degree is the You mentioned that 45% of all dendritic protrusions looked like filopodia”
    — Ceilidh ... To Dr. Shim, mcmaster.ca

  • “Online pharmacy blog. Tuesday, September 8, 2009. Crucial Gene For Mental Development. In laying down the nervous circuitry of the assured that the nerve cells organized the finger-like filopodia which barricaded migration by hastening too a lot of branches”
    — Pharmacy blog : Crucial Gene For Mental Development,

  • “"CDC five" report from Los Angeles spurs public health panic " in the stochastic organization of filopodia. Immunostaining of modified histones defines”
    — Δεν έχει οριστεί κανένα φόρουμ. | NotAIDS!,

  • “Fluorescent stain delivery system using non-toxic polymer nanoparticles for endocytotic absorption by living cells and subsequent delivery of stain to cell structures and components”
    — Dr Irene Canton - How I use CelLuminate™ - Fluorescent stain,

  • “oilspill 3D article-level metrics bacteria Blog Pick of the Month Blogs bluefin tuna Topographical Patterns: Influence of Filopodia and Focal Adhesions on”
    — Blog Pick Of The Month | EveryONE,

  • “ increases markedly at the point of contact between filopodia reaching out from healthy cells and the plasma Mothes also suggested a model of filopodia down-regulation involving the receptors that localize to the tips of these structures”
    — The Scientist : NewsBlog Print: Surf's up for viruses, the-

  • “Views presented on this blog and all other online spaces are mine and Sean Carroll - all started early, form gradually evolved into a "blog"”
    — Quick Links | A Blog Around The Clock,

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